Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4615)
Related Products (4615)
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5-endo-Hydroxyborneol
0 ImagesCat. No.: HY-N16572CAS No.: 68738-10-35-endo-Hydroxyborneol is a hydroxylation metabolite of a monoterpene compound. 5-endo-Hydroxyborneol can be used as a drug intermediate to synthesize optically pure compounds.
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Fmoc-PNA-U-OH
0 ImagesCat. No.: HY-W665456CAS No.: 959151-70-3Fmoc‑PNA‑U‑OH is a peptide nucleic acid monomer that can be used for the synthesis of peptide nucleic acids (PNAs). Fmoc‑PNA‑U‑OH exhibits specific binding to adenine, resistance to enzymatic degradation, and strong hybridization properties. Fmoc‑PNA‑U‑OH can be applied in research fields such as gene diagnosis, molecular biology, and antisense therapy.
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pCR8
0 ImagesCat. No.: HY-174460pCR8 is a prodrug of CR8 (HY-18340). pCR8 is amphiphilic and can self-assemble into nanoparticles. pCR8 can release CR8 under the action of high concentration of H2O2 in the tumor microenvironment. CR8 is a molecular glue degrader that can effectively degrade cell cycle-related proteins and has antitumor activity. pCR8 can be used in the research of tumors such as breast cancer.
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5-Hydroxyisatin
0 ImagesCat. No.: HY-W092549CAS No.: 116569-09-65-Hydroxyisatin can be used to synthesize anti-cancer agents.
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1-Amino-3-(phosphonooxy)-2-propanone
0 ImagesCat. No.: HY-176959CAS No.: 205189-34-01-Amino-3-(phosphonooxy)-2-propanone is a drug intermediate that can be used for the synthesis of vitamin B6.
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L-Cystine N-carboxyanhydride
0 ImagesCat. No.: HY-44680CAS No.: 51507-96-1L-Cystine N-carboxyanhydride can be used for synthesis of polyamino acid carrier for anti-tumor agent delivery.
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Cys-CPP44
0 ImagesCat. No.: HY-P11926Cys-CPP44 is a cell-penetrating peptide with a Cys introduced at the N-terminus, which can specifically penetrate hepatocellular carcinoma cells. Modification with Cys-CPP44 promotes the specific penetration of arsenic trioxide-loaded liposomes into hepatocellular carcinoma cells and enhances the cellular uptake of liposomes by these cells. Cys-CPP44 can be used for the research of hepatocellular carcinoma.
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Antiproliferative agent-3
0 ImagesCat. No.: HY-145866Antiproliferative agent-3 is an antiproliferative agent. Antiproliferative agent-3 exhibits anticancer activity against a variety of cancers, including estrogen receptor-positive breast cancer. Antiproliferative agent-3 shows no toxicity to wild-type zebrafish embryos. Antiproliferative agent-3 can be used in the research of chronic myeloid leukemia, promyelocytic leukemia, Burkitt's lymphoma, estrogen receptor-positive mammary adenocarcinoma, cervical cancer, and lung cancer.
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FI-3
0 ImagesCat. No.: HY-N16458CAS No.: 1316171-50-2FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics.
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4,7-Dichloroquinoline-15N
0 ImagesCat. No.: HY-59243SCAS No.: 366495-92-34,7-Dichloroquinoline-15N is the 15N labeled 4,7-Dichloroquinoline (HY-59243). 4,7-Dichloroquinoline is a dichloro-substituted quinoline that can be used for the synthesis of other active compounds.
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Euchrenone B1
0 ImagesCat. No.: HY-N20709CAS No.: 119061-09-5Euchrenone B1 is a flavonoid. Euchrenone B1 can be isolated from the stem bark of Maackia amurensis and the roots of Euchresta formosana. Euchrenone B1 exhibits anticancer activity against cervical cancer, melanoma, breast cancer, and liver cancer.
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Elsulfavirine sodium
0 ImagesCat. No.: HY-109056ACAS No.: 867365-40-0Synonyms: R-1206 sodiumElsulfavirine sodium (R-1206) is an orally active human carbonic anhydrase (carbonic anhydrase, CA) inhibitor and an allosteric inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRT). Elsulfavirine sodium also targets and blocks the interaction between adenylosuccinate lyase (ADSL) and insulin-induced gene proteins INSIG1/2, blocks SREBP-1-mediated de novo lipid synthesis, and inhibits the proliferation of liver cancer cells. The combination of Elsulfavirine sodium and Lenvatinib (HY-10981) produces a synergistic anti-tumor effect. Elsulfavirine sodium is converted into the active metabolite VM1500A in vivo, blocks the DNA polymerase activity of reverse transcriptase, and inhibits HIV-1 replication. Elsulfavirine sodium exhibits a Ki of 1960 nM-52400 nM against human carbonic anhydrase isoforms including I, VII, VI, VA, VB, IX, XIII, XIV. Elsulfavirine sodium is used in studies related to HIV-1 infection and liver cancer.
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N-Ethylnicotinamide
0 ImagesN-Ethylnicotinamide is a compound with weak vasodilatory activity. N-Ethylnicotinamide also serves as the core scaffold of the antianginal agent Nicorandil (HY-B0341) and its derivatives.
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H-Tyr-Gly-OH
0 ImagesCat. No.: HY-W343771CAS No.: 673-08-5H-Tyr-Gly-OH is an amino acid building block commonly used in biochemical and peptide synthesis.
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Atorvastatin acetonide tert-butyl ester (Standard)
0 ImagesAtorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
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Bibenzyl
0 ImagesBibenzyl (s-Diphenylethane; Dibenzyl) is the parent core structure of bibenzyl-type natural products and an intermediate in organic synthesis. Hydroxyl-substituted derivatives of Bibenzyl are mainly isolated from plants such as Dendrobium (Orchidaceae) and Cannabaceae. These derivatives accumulate when plants are exposed to fungal infection and biotic stress, and exhibit antioxidant, anti-inflammatory, and anti-hepatic steatosis activities.
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Fingolimod impurity 3
0 ImagesCat. No.: HY-108399CAS No.: 162358-08-9
